“Many important biological processes occur in three dimensions and on millisecond timescales,” says Lars Hufnagel on the rationale for developing the new microscope.
“Our new method allows us to study processes both in 3D and on timescales of 200 images per second,” says Robert Prevedel. Lars Hufnagel adds: “On top of that, it delivers up to ten times better, namely truly isotropic, resolution than classic light field microscopy.”
First feasibility study on fish heart
Interdisciplinary research and development
“This new microscope demonstrates that EMBL is not only at the forefront of molecular biology research but also an important place to research and develop new technologies needed within the field,” says Hufnagel.
Next step: neurons
“Future camera developments can further increase the imaging speed. This would make our new microscope technique an attractive tool to study the dynamics within small neuronal networks on millisecond time scales in 3D,” concludes Prevedel.